Fisher SA, Pavan J, Villa-Tamayo MF, Fabris C, Conboy NE, Niznik C, Yee LM, Moscoso-Vasquez M, Batista AFMB, Kohn MA, Kobayashi E, Majithia AR, Huang J, Tian T, Aaron RE, Klonoff D. Continuous glucose monitoring and maternal and neonatal morbidity in pregnant people with type 1 diabetes. J Diabetes Sci Technol.19322968251388119 (2025). DOI. PDF
Yu CJ, Pessentheiner AR, Liu S, Wax S, Maciej-Hulme ML, Painter CD, Ramms B, Sandoval DR, Quach A, DeForest N, Ducasa GM, Tognaccini C, Labib C, Al-Azzam N, Haumann F, Trieger G, Secrest P, Majithia AR, Petrey AC, Godula K, Atkins AR, Downes M, Evans RM, Gordts PLSM. Adipocyte heparan sulfate determines Type 2 diabetes susceptibility in mice via FGF1-mediated glucose regulation. Mol. Metab. 102267 (2025). DOI. PDF
Pinson K, Kim JJ, Sharma N, Kobayashi E, Majithia AR, Stanly V, Ramos GA. Characterizing glucose in labor: Continuous glucose monitoring in parturients without diabetes. Pregnancy (Hoboken) 1, e70108 (2025). DOI. PDF
Cunha e Rocha K, Tan B, Kempf J, Medina C, Beldona V, Qian C, Duan Y, Xiang Q, Yoo A, Du X, Majithia AR, Ying W. Adipose tissue macrophage-derived miR-690 modulates adipocyte precursor cell maintenance and adipogenesis. Molecular Metabolism. 2025;102246. DOI. PDF
Kobayashi E, Linden-Santangeli NJ, Chan N, Toomey CB, Mudaliar S, Temprosa M, Edelstein S, Goyal R, Rangamani P, Majithia AR; for the Diabetes Prevention Program Research Group. Longitudinal Metabolic Trajectories in Diabetes Prevention Program Participants Reveal Subgroups With Varying Micro- and Macrovascular Complication Risks. Diabetes Care. 2025;250866. DOI. PDF
Díaz LA, Alazawi W, Agrawal S, Arab JP, Arrese M, Idalsoaga F, Barreyro FJ, Gadano A, Marciano S, Martínez Morales J, Villela-Nogueira C, Leite N, Couto CA, Theodoro R, Monteiro M, Oliveira CP, Pessoa MG, Alvares-da-Silva MR, Madamba E, Bettencourt R, Richards LM, Majithia AR, Khera AV, Loomba R, Ajmera V. High Inherited Risk Predicts Age-Associated Increases in Fibrosis in Patients with MASLD. Journal of Hepatology. 2025;0(0). DOI. PDF
Ramesh G, Kobayashi E, Sharma N, Majithia AR, Kulasa K, Boeder SC. Accuracy of factory-calibrated continuous glucose monitors in critically ill patients receiving intravenous insulin: a prospective clinical trial of two leading systems. Journal of Diabetes Science and Technology. 2025 May. Online ahead of print. DOI. PDF
Du X, Mendez-Lara K, Hu S, Diao R, Bhavimani G, Hernandez R, Glass K, De Arruda Saldanha C, Flannick J, Heinz S, Majithia AR. An alternatively translated isoform of PPARG proposes AF-1 domain inhibition as an insulin sensitization target. Diabetes. 2025 Jan 24;db240497. DOI. PDF
Begzati A, Godinez-Macias KP, Long T, Watrous JD, Moranchel R, Kantz ED, Tuomilehto J, Havulinna AS, Niiranen TJ, Jousilahti P, Salomaa V, Yu B, Norby F, Rebholz CM, Selvin E, Winzeler EA, Cheng S, Alotaibi M, Goyal R, Ideker T, Jain M, Majithia AR. Plasma Lipid Metabolites, Clinical Glycemic Predictors, and Incident Type 2 Diabetes. Diabetes Care. 2025 Jan 6;48(3):1-8. DOI. PDF
2024
DeForest N, Wang Y, Zhu Z, Dron JS, Koesterer R, Natarajan P, Flannick J, Amariuta T, Peloso GM, Majithia AR. Genome-wide discovery and integrative genomic characterization of insulin resistance loci using serum triglycerides to HDL-cholesterol as a proxy. Nature Communications. 2024 Sep 14;15(1):8068. DOI. PDF
2023
DeForest N, Kavitha B, Hu S, Isaac R, Krohn L, Wang M, Du X, Saldanha CDA, Gylys J, Merli E, Abagyan R, Najmi L, Mohan V, Alnylam Human Genetics, AMP-T2D Consortium, Flannick, J, Peloso GM, Gordts P, Heinz S, Deaton AM, Khera AV, Olefsky J, Radha V, Majithia, AR. Human gain-of-function variants in HNF1A confer protection from diabetes but independently increase hepatic secretion of atherogenic lipoproteins. Cell Genomics. (2023) 3(7) 100339. DOI. PDF
Trieger G, Pessentheiner A, Purcell S, Green C, DeForest N, Willert K, Majithia AR, Metallo C, Godula K, Gordts P. Glycocalyx engineering with heparan sulfate mimetics attenuates Wnt activity during adipogenesis to promote glucose uptake and metabolism. J. Biol. Chem. (2023) 299(5) 104611. DOI. PDF
Boeder S, Kobayashi E, Ramesh G, Serences B, Kulasa K, Majithia, AR. Accuracy and Glycemic Efficacy of Continuous Glucose Monitors in Critically Ill COVID-19 Patients: a Retrospective Study. Journal of Diabetes Science and Technology. (2022 Epub). 2023:17(3) 642-648. DOI. PDF
2022
Isaac R, Vinik Y, Mikl M, Shatz-Azoulay H, Yaakobi A, DeForest N, Majithia AR, Webster N, Elhanany E, Zick Y. A Seven-Transmembrane Protein -TM7SF3, Resides in Nuclear Speckles and Regulates Alternative Splicing. iScience. (2022). DOI. PDF
Majithia AR, Erani DM, Kusiak CM, et al. Medication Optimization Among People With Type 2 Diabetes Participating in a CGM-Driven Virtual Care Program: Prospective Trial. JMIR Formative Research. 2022 Feb. DOI. PDF
DeForest N, Majithia, AR. Genetics of Type 2 Diabetes: Implications from Large-Scale Studies. Curr Diab Rep. 22, 227–235 (2022). DOI. PDF
2021
Du X, DeForest N, Majithia AR. Human Genetics to Identify Therapeutic Targets for NAFLD: Challenges and Opportunities. Frontiers in Endocrinology. 2021 Dec;12:1500. DOI. PDF
Bergenstal RM, Layne JE, Zisser H, Gabbay RA, Barleen NA, Lee AA, Majithia AR, Parkin CG, Dixon RF. Remote Application and Use of Real-Time Continuous Glucose Monitoring by Adults with Type 2 Diabetes in a Virtual Diabetes Clinic. Diabetes Technol Ther. 2021 Feb;23(2):128-132. DOI. PDF
2020
Majithia AR, Kusiak CM, Armento Lee A, Colangelo FR, Romanelli RJ, Robertson S, Miller DP, Erani DM, Layne JE, Dixon RF, Zisser H. Glycemic Outcomes in Adults With Type 2 Diabetes Participating in a Continuous Glucose Monitor–Driven Virtual Diabetes Clinic: Prospective Trial. J Med Internet Res 2020;22(8):e21778. DOI. PDF
Dixon RF, Zisser H, Layne JE, Barleen NA, Miller DP, Moloney DP, Majithia AR, Gabbay RA, Riff J. A Virtual Type 2 Diabetes Clinic Using Continuous Glucose Monitoring and Endocrinology Visits. J Diabetes Sci Technol. 2020;14(5):908-911. DOI. PDF
Jia T, Munson B, Lango Allen H, Ideker T, Majithia AR. Thousands of missing variants in the UK Biobank are recoverable by genome realignment. Ann Hum Genet. 2020 Mar; 84: 214– 220. DOI. PDF
Lal D, May P, Perez-Palma E, Samocha KE, Kosmicki JA, Robinson EB, Møller RS, Krause R, Nürnberg P, Weckhuysen S, De Jonghe P, Guerrini R, Niestroj LM, Du J, Marini C; EuroEPINOMICS-RES Consortium, Ware JS, Kurki M, Gormley P, Tang S, Wu S, Biskup S, Poduri A, Neubauer BA, Koeleman BPC, Helbig KL, Weber YG, Helbig I, Majithia AR, Palotie A, Daly MJ. Gene family information facilitates variant interpretation and identification of disease-associated genes in neurodevelopmental disorders. Genome Med 12, 28 (2020). DOI. PDF
2019
Jaiswal P, Majithia AR, Rosel D, Liao XH, Khurana T, Kimmel AR. Integrated actions of mTOR complexes 1 and 2 for growth and development of Dictyostelium. Int J Dev Biol. 2019;63(8-9-10):521-527. DOI. PDF
Jiao Y, Ahmed U, Sim MFM, Bejar A, Zhang X, Talukder MMU, Rice R, Flannick J, Podgornaia AI, Reilly DF, Engreitz JM, Kost-Alimova M, Hartland K, Mercader JM, Georges S, Wagh V, Tadin-Strapps M, Doench JG, Edwardson JM, Rochford JJ, Rosen ED, Majithia AR. Discovering metabolic disease gene interactions by correlated effects on cellular morphology. Mol Metab. 2019 Jun; 24:108-119. Epub 2019 Mar 13. DOI. PDF
Broekema MF, Massink MPG, Donato C, de Ligt J, Schaarschmidt J, Borgman A, Schooneman MG, Melchers D, Gerding MN, Houtman R, Bonvin AMJJ, Majithia AR, Monajemi H, van Haaften GW, Soeters MR, Kalkhoven E. Natural helix 9 mutants of PPARγ differently affect its transcriptional activity. Mol Metab. 2019 Feb;20:115-127. DOI. PDF